A Cellular Reset for Stressed Skin

Why We Created It

At Bionassay, every formula begins with lived experience. As a Caribbean woman, I’ve felt the sting of sunburns and the redness that lingers after treatments meant to make skin healthier. My partner, Bionassay’s co-founder, has spent years in regenerative cosmetics, where it became clear that the industry lacked a true recovery tool — one that helps skin heal as much as it beautifies.

We created CYTOGEN Masque to go beyond surface glow. It’s designed to comfort stressed skin — whether from the sun, cosmetic procedures, aging, or daily life — while strengthening the barrier for the long term. Think of it as a “second skin”: a biocellulose veil infused with biosignaling peptides to help your skin reset, repair, and return to balance.

Meet CYTOGEN Masque

CYTOGEN Masque is a regenerative treatment, not just a glow mask. Its biocellulose base acts like a breathable second skin, ensuring deep delivery of actives with clinical precision.

At the heart of the formula is Bovine Milk Secretome, rich in biosignaling peptides and cytokines such as TGF-β, which activate the skin’s natural repair mechanisms. Around this, we layered actives known for soothing and resilience:

Allantoin – calms and reduces sensitivity
Ectoin – shields against oxidative and environmental stress
Niacinamide – strengthens the barrier and refines texture
Escin – reduces redness and supports circulation

Together, they create a treatment that restores, soothes, and hydrates — leaving skin stronger, calmer, and visibly renewed.

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Benefits

Barrier Repair

Restores the skin’s natural defense system, helping it recover from stress and external aggressors.

Strengthens Resilience

Boosts skin’s ability to withstand future damage while supporting healthy cell turnover.

Calming & Soothing

Visibly reduces redness, irritation, and sensitivity — making it an ideal post-procedure ally.

Intelligent Hydration

Delivers lasting moisture for skin that feels plump, supple, and rejuvenated.

Made in Switzerland

Switzerland’s legacy of precision and purity guided the creation of CYTOGEN Masque. Produced under rigorous third-party lab testing, each mask is crafted to the highest standards of safety and efficacy. Advanced biotechnology preserves the full power of bovine milk secretome, ensuring it delivers maximum restorative benefit.

This is skincare built with integrity: science-driven, meticulously crafted, and uncompromising in quality.

The Science of Bovine Milk Secretome

Extracted through advanced biotechnological processes, the Bovine Milk Secretome is a complex of peptides and cytokines that mimic the skin’s own communication molecules to reactivate natural repair pathways.

Rich in TGF-β, it stimulates collagen synthesis, calms inflammation, and accelerates barrier recovery. Its biocompatibility allows the skin to recognize and respond naturally, creating a regenerative environment that soothes instantly and strengthens over time.

The Science of Biocellulose Fibers

Biocellulose is a fiber thinner than natural cellulose, originally developed for medical wound care and prized for its ability to adhere perfectly to the skin, creating a breathable second layer that feels almost invisible.

Its high absorbency allows it to retain and gradually release concentrated active ingredients for maximum effectiveness.

In CYTOGEN Masque, this fiber becomes a delivery system of precision, enhancing penetration and merging performance with sensorial comfort.

In‑Vitro Data That Moves Fast, Like Your Skin

CYTOGEN Masque accelerated keratinocyte gap closure in a standard scratch assay, reaching near-complete closure as early as 32 hours at the lowest tested dose (0.3 mg/mL).

In-vitro study in HaCaT keratinocytes.

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Signaling: How the Skin Communicates

Even though signaling starts at the surface, it creates a cascade of communication that continues through the deeper layers — teaching the skin to repair, renew, and strengthen itself from within.

Trigger & Receptivity

Skin signaling is the body’s natural repair language — messages exchanged between cells through peptides, cytokines, and growth factors. It can be triggered internally by the skin’s own cells or externally through bioactive formulas like the Bovine Milk Secretome in CYTOGEN Masque.

When the skin is slightly stressed — after exfoliation, procedures, or environmental exposure — its permeability and receptivity increase, allowing these signals to travel deeper and work more efficiently.

Epidermis

The Activation Layer

Signaling begins here. Niacinamide and Ectoin strengthen the barrier while biocellulose fibers create a second-skin veil, optimizing absorption and locking in hydration.

Dermis

The Regenerative Layer

Messages cascade downward. Bovine Milk Secretome, rich in TGF-β and peptides, stimulates fibroblasts, collagen synthesis, and cell renewal, supported by Allantoin and Escin to soothe and improve circulation.

Hypodermis

The Supportive Layer

While actives rarely reach this depth, CYTOGEN’s hydration gradient allows water and nutrients to diffuse progressively, enhancing elasticity and overall skin comfort.

Designed for Modern Beauty Rituals

Skin stress comes in many forms: the heat of the sun, the flush after treatments, the sensitivity of aging, or the toll of daily lifestyle stress. CYTOGEN Masque was designed for all of them.

Its biocellulose veil soothes on contact while regenerative actives work beneath the surface. The result: skin that looks calmer instantly and grows more resilient with time.

This is beauty reimagined for today’s world — science and ritual combined, so you can enjoy spa-like recovery in the comfort of your own home.

The Various Types of Skin Inflammation & Irritation

While inflammation is part of the skin’s natural healing response, chronic or repeated irritation can weaken the barrier, leading to redness, dryness, or heightened sensitivity. CYTOGEN Masque helps calm, rebalance, and restore comfort across multiple forms of inflammation.

Reactive Inflammation

Triggered by: cosmetic treatments, exfoliants, or overuse of actives.

How it appears: redness, heat, and tightness after procedures or product application.

How CYTOGEN helps: Bovine Milk Secretome’s cytokines and peptides modulate the inflammatory response, helping the skin return to equilibrium while Allantoin and Ectoin soothe and strengthen the barrier.

Environmental Irritation

Triggered by: UV exposure, pollution, wind, or climate fluctuations.

How it appears: surface dryness, itching, dullness, or sensitivity.

How CYTOGEN helps: Ectoin shields cells from oxidative stress, while Niacinamide reinforces the epidermal barrier, improving resilience and hydration retention.

Micro-Inflammation from Aging

Triggered by: internal oxidative stress and slowed cellular turnover.

How it appears: persistent low-grade redness, loss of firmness, or uneven tone.

How CYTOGEN helps: TGF-β peptides from the Bovine Milk Secretome stimulate fibroblast activity and collagen renewal, reducing inflammatory mediators and restoring a smoother, healthier-looking skin texture.

Sensory or Stress-Induced Irritation

Triggered by: emotional stress or nervous system sensitivity.

How it appears: flushed, sensitized, or prickly skin without visible damage.

How CYTOGEN helps: the biocellulose veil provides instant cooling and relief, while biosignaling peptides calm neurogenic inflammation and help stabilize reactive skin responses.

Not Just Glow — Cellular Reset

CYTOGEN Masque moves beyond superficial radiance. It’s a barrier reset rooted in regenerative science — helping skin recover, renew, and build lasting resilience.